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Published on: April 17, 2012
Eosinophilic granuloma of the sacrum treated with radiation therapy: a case report
David B Bumpass1, Andrew Park1, Kirk T Hill2
1Department of Orthopaedic Surgery, Washington University, 660 S. Euclid Ave, Campus Box 8233, St. Louis, MO 63110, USA.
Background Context:
Eosinophilic granulomas (EGs) of the sacrum have been reported in fewer than 10 patients. Treatment algorithms for these tumors remain poorly defined; there are no reports of treating solitary sacral EG with radiation therapy (RT).
Purpose:
This study aimed to describe the presentation, treatment, and outcome of sacral EG in an adult patient with intractable pain and radiculopathy, treated in a novel fashion with RT.
Study Design/Setting:
The study design was a case report from a tertiary cancer referral center.
Methods:
Patient records, imaging, and pathology were reviewed.
Results:
A 35-year-old man received 20 Gy of radiation to his S1 EG lesion. He subsequently developed vertebra plana of S1 causing symptomatic L5-S1 stenosis, but 15 months after RT treatment was free of pain or tumor recurrence.
Conclusion:
Radiation therapy is an effective treatment option for sacral EG causing severe axial pain and neural impingement.
