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Related Concept Videos

Ureters01:22

Ureters

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The ureters are retroperitoneal tubes located on either side of the vertebral column. They are responsible for transporting urine from each kidney to the urinary bladder. These tubes have thick walls and are approximately 25-30 cm long. Their diameter is around 10 mm at the renal pelvis, gradually narrowing to 1 mm as the ureter obliquely enters the posterior bladder wall through the ureteric orifices. The shape of these orifices is slit-like, which helps to prevent urine backflow toward the...
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Anatomy of the Genitourinary System I: Kidneys and Ureters01:11

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The upper urinary system comprises two kidneys and two ureters, which are crucial in filtering blood and forming urine.KidneysLocation and Structure:The kidneys are two bean-shaped organs positioned behind the peritoneum on either side of the spine.Kidneys are between the 12th thoracic (T12) and the 3rd lumbar (L3) vertebrae.The position of the liver causes the right kidney to sit slightly lower than the left.Protective Layers:Each kidney is enveloped in a tough, fibrous membrane called the...
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Kidney Transplant II: Surgical Procedure01:26

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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
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Related Experiment Video

Updated: Apr 3, 2026

Surgical Model for Single-Staged Tissue-Engineered Urothelial Tubes in Minipigs
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Published on: July 5, 2024

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[URETERAL TISSUE ENGINEERING: CHALLENGES AND PROSPECTS].

P V Glybochko, Ju G Alaev, A Z Vinarov

    Urologiia (Moscow, Russia : 1999)
    |September 23, 2015
    PubMed
    Summary

    Tissue engineering shows promise for ureter reconstruction, utilizing natural or synthetic matrices with or without cells. While preclinical studies are encouraging, clinical trials are still needed for ureteral repair.

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    Area of Science:

    • Urology
    • Biomaterials Science
    • Regenerative Medicine

    Context:

    • Ureteral reconstruction presents significant challenges in urological surgery.
    • Existing reconstructive techniques for ureteral impairments are diverse, highlighting the need for novel approaches.
    • Tissue engineering offers a promising new avenue for addressing complex ureteral conditions.

    Purpose:

    • To review preclinical findings on the feasibility of tissue engineering for ureter reconstruction.
    • To evaluate the use of natural and synthetic matrices in ureteral tissue engineering.
    • To assess the current status and future directions of tissue engineering for ureteral repair.

    Summary:

    • This review synthesizes results from preclinical studies investigating tissue engineering for various ureteral pathologies.
    • It explores the application of both natural and synthetic biomaterials as matrices, with or without cellular components.
    • Current research focuses on preclinical assessments, with no reported clinical trials for ureteral tissue engineering.

    Impact:

    • Preclinical data suggest optimism for tissue-engineered ureteral repair.
    • Highlights the complexity and need for meticulous preclinical study design in ureteral tissue engineering.
    • Identifies tissue engineering as a developing field for reconstructive urology, pending further clinical validation.