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Related Experiment Video

Updated: Apr 3, 2026

Methods to Explore the Influence of Top-down Visual Processes on Motor Behavior

Methods to Explore the Influence of Top-down Visual Processes on Motor Behavior

Published on: April 16, 2014

Perspective.

Lewis Wolpert¹

¹Department of Cell and Developmental Biology, University College London, London WC1E 6BT, United Kingdom;

Annual Review of Cell and Developmental Biology

|September 23, 2015

Summary

This summary is machine-generated.

This research explores developmental biology, focusing on cell division mechanics and embryonic patterning. Key findings relate to positional information in embryo development and chick limb morphogenesis.

Keywords:

Autobiography cleavage development embryo limb positional information regeneration

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Area of Science:

Developmental Biology
Cellular Mechanics
Embryogenesis

Background:

Transition from civil engineering to developmental biology.
Initial research in soil mechanics before shifting focus.
PhD research on the mechanics of cell division.

Purpose of the Study:

Investigate the mechanisms of embryonic patterning.
Explore the role of positional information in development.
Study the morphogenesis of the chick limb.

Main Methods:

PhD research at Kings College on cell division.
Studies on sea urchin embryo morphogenesis.
Research on chick limb development at Middlesex Hospital Medical School.

Main Results:

Proposed positional information as a fundamental mechanism for embryonic patterning.
Gained insights into the mechanics of cell division.
Detailed the process of chick limb development.

Conclusions:

Positional information is a key principle in understanding how embryos are patterned.
The study of cell division mechanics is crucial for developmental biology.
Chick limb development provides a model for studying complex morphogenetic processes.