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Related Concept Videos

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Reticular Dermis01:15

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The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
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Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
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Cells of the Epidermis01:24

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The epidermis is made of four or five layers of epithelial cells, depending on its location in the body. From deep to superficial, these layers are the stratum basale, stratum spinosum, stratum granulosum, stratum lucidum, and stratum corneum.
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Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
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Updated: Apr 3, 2026

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
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Annular lichenoid syphilis: A rare entity.

Ananta Khurana1, Archana Singal1, Seema Gupta2

  • 1Department of Dermatology and STD, University College of Medical Sciences and GTB Hospital (University of Delhi), New Delhi, India.

Indian Journal of Sexually Transmitted Diseases and AIDS
|September 24, 2015
PubMed
Summary
This summary is machine-generated.

Lichenoid syphilis, a rare form of secondary syphilis, presents diagnostic challenges due to its varied skin manifestations. This case highlights localized annular lichenoid lesions on the neck, emphasizing the need for awareness in syphilis diagnosis.

Keywords:
Annularlichenoidsyphilis

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Area of Science:

  • Dermatology
  • Infectious Diseases
  • Syphilology

Background:

  • Syphilis remains a global health concern, notorious for its diverse clinical presentations.
  • Secondary syphilis frequently mimics other dermatological conditions, complicating diagnosis.
  • Lichenoid syphilis is an infrequent variant, rarely documented even in the antibiotic era.

Observation:

  • A 32-year-old female patient presented with a specific dermatological issue.
  • The patient exhibited localized annular lichenoid lesions.
  • The lesions were predominantly situated on the neck.

Findings:

  • The presented case is identified as lichenoid syphilis.
  • The clinical presentation involved annular, lichenoid lesions.
  • The location was localized to the neck.

Implications:

  • This case underscores the importance of considering syphilis in the differential diagnosis of dermatological disorders.
  • Increased awareness of uncommon presentations like lichenoid syphilis is crucial for timely diagnosis and treatment.
  • Further research into the varied manifestations of syphilis can improve diagnostic accuracy and patient outcomes.