Related Experiment Video

Updated: Apr 3, 2026

Analysis of Single-cell Gene Transcription by RNA Fluorescent In Situ Hybridization FISH
13:06

Analysis of Single-cell Gene Transcription by RNA Fluorescent In Situ Hybridization FISH

Published on: October 7, 2012

16.2K

Fusariosis

Fabio Nucci1, Simone A Nouér2, Domenico Capone2

  • 1Hematology Service, University Hospital, Universidade Federal Fluminense, Niteroi, Brazil.

Seminars in Respiratory and Critical Care Medicine
|September 24, 2015
PubMed

Insights

Fusarium species cause lung infections, particularly pneumonia in immunocompromised patients. Treatment involves voriconazole or liposomal amphotericin B, with outcomes depending on immune recovery.

Area of Science:

  • Mycology
  • Infectious Diseases
  • Pulmonology

Background:

  • Fusarium species are common causes of superficial fungal infections like onychomycosis and keratitis.
  • They can also cause invasive diseases, including pulmonary infections (fusariosis).

Purpose of the Study:

  • To describe the clinical spectrum, radiologic findings, and treatment outcomes of pulmonary fusariosis.
  • To differentiate fusariosis from invasive aspergillosis in immunocompromised hosts.

Main Methods:

  • Review of clinical cases and radiologic findings of patients with pulmonary fusariosis.
  • Analysis of treatment regimens and patient outcomes.

Main Results:

  • Fusarial pneumonia predominantly affects severely immunocompromised individuals, especially those with acute leukemia or undergoing stem cell transplantation.
  • Radiologic findings mimic invasive aspergillosis but are often accompanied by disseminated skin lesions and positive blood cultures.
  • Voriconazole or liposomal amphotericin B are primary treatments, but outcomes are generally poor, linked to immune reconstitution.

Conclusions:

  • Pulmonary fusariosis is a severe infection in immunocompromised patients with a high mortality rate.
  • Early diagnosis and appropriate antifungal therapy are crucial, but host immune status recovery is paramount for survival.

More Related Videos

Combined Recombinase Polymerase Amplification CRISPR/Cas12a Assay for Detecting Fusarium oxysporum f. sp. cubense Tropical Race 406:47

Combined Recombinase Polymerase Amplification CRISPR/Cas12a Assay for Detecting Fusarium oxysporum f. sp. cubense Tropical Race 4

Published on: November 14, 2025

348
Standard Membrane Feeding Assay for the Detection of Plasmodium falciparum Infection in Anopheles Mosquito Vectors05:28

Standard Membrane Feeding Assay for the Detection of Plasmodium falciparum Infection in Anopheles Mosquito Vectors

Published on: May 12, 2022

3.8K

Related Concept Videos

Symbiosis00:58

Symbiosis

Symbiotic relationships are long-term, close interactions between individuals of different species that affect the distribution and abundance of those species. When a relationship is beneficial to both species, this is called mutualism. When the relationship is beneficial to one species but neither beneficial nor harmful to the other species, this is called commensalism. When one organism is harmed to benefit another, the relationship is known as parasitism. These types of relationships often...
38.6K
Diversity of Protists II01:27

Diversity of Protists II

Alveolates are a group of organisms recognized by the presence of alveoli, which are cytoplasmic sacs located beneath the cell membrane. While their function remains uncertain, alveoli may help regulate water balance by controlling how much water enters and leaves the cell. In dinoflagellates, these structures may serve as armor plates. There are three major types of alveolates: ciliates, which move using cilia; dinoflagellates, which use flagella for movement; and apicomplexans, which are...
2.2K
Anthelminthic Agents01:15

Anthelminthic Agents

Anthelmintic drugs differ significantly from antiparasitic therapies targeting protozoa, primarily due to differences in parasite biology. Whereas most protozoal treatments act on proliferating cells, anthelmintics are typically directed against mature, nonproliferative helminths. The therapeutic approach considers the helminth's reliance on neuromuscular coordination, glucose metabolism, and microtubular integrity for survival, reproduction, and localization within the host. Most anthelmintics...
50
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
716