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Magnesium in Prevention and Therapy
Uwe Gröber1, Joachim Schmidt2, Klaus Kisters3,4
1Academy of Micronutrient Medicine, Essen 45130, Germany. uwegroeber@gmx.net.
Nutrients
|September 26, 2015
Summary
Magnesium is vital for over 300 bodily functions, including energy metabolism and DNA synthesis. Low magnesium levels are linked to chronic diseases like Alzheimer's, cardiovascular disease, and ADHD.
Area of Science:
- Biochemistry
- Human Physiology
Background:
- Magnesium is the fourth most abundant mineral in the human body.
- It acts as a cofactor for over 300 enzymatic reactions, crucial for adenosine triphosphate (ATP) metabolism.
Purpose of the Study:
- To highlight the essential roles of magnesium in the body.
- To discuss the implications of magnesium imbalances, particularly hypomagnesemia.
- To explore the association between low magnesium levels and various chronic diseases.
Main Methods:
- Literature review of magnesium's biochemical and physiological functions.
- Analysis of studies linking magnesium status to disease prevalence.
Main Results:
- Magnesium is essential for DNA/RNA synthesis, protein synthesis, and regulating muscular contraction, blood pressure, insulin metabolism, cardiac excitability, vasomotor tone, nerve transmission, and neuromuscular conduction.
- Hypomagnesemia can lead to neuromuscular, cardiac, and nervous disorders.
- Low magnesium levels are associated with chronic conditions including Alzheimer's disease, insulin resistance, type-2 diabetes mellitus, hypertension, cardiovascular disease, stroke, migraine headaches, and ADHD.
Conclusions:
- Magnesium plays a critical role in maintaining overall health.
- Adequate magnesium levels are important for the prevention and treatment of numerous chronic diseases.
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