Multi-Facial, Non-Peptidic α-Helix Mimetics
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Updated: Apr 3, 2026

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Solid-phase Submonomer Synthesis of Peptoid Polymers and their Self-Assembly into Highly-Ordered Nanosheets
Published on: November 2, 2011
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Maryanna E Lanning1, Steven Fletcher2,3
1Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, 20 N. Pine St., Baltimore, MD 21201, USA. mlanning@umaryland.edu.
Biology
|September 26, 2015
Abstract:
α-Helices often recognize their target proteins at protein-protein interfaces through more than one recognition face. This review describes the state-of-the-art in the design of non-peptidic α-helix mimetics that reproduce functionality from multiple faces of an α-helix.

