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Iron Deficiency Anemia in Pregnancy
1Department of Obstetrics and Gynaecology, University Hospital Zurich, Obstetric Research, Feto- Maternal Haematology Research Group, Zurich, Switzerland.
Seminars in Hematology
|September 26, 2015
Summary
Anemia in pregnancy, often due to iron deficiency, poses risks to mothers and fetuses. Treatment involves oral or intravenous iron to manage this common obstetric complication.
Area of Science:
- Obstetrics and Perinatal Care
- Hematology
Background:
- Anemia is a frequent complication in obstetrics and perinatal care.
- Defined as hemoglobin below 10.5 g/dL, anemia in pregnancy has diverse causes including nutritional deficiencies, infections, and inherited red blood cell disorders.
- Iron deficiency is the predominant cause, affecting an estimated 20%-80% of pregnant women globally.
Purpose of the Study:
- To review the causes, consequences, and management of anemia in pregnancy.
- To highlight the specific risks associated with anemia for both maternal and fetal outcomes.
- To discuss therapeutic strategies for pregnancy anemia.
Main Methods:
- Literature review of anemia in obstetrics and perinatal care.
- Analysis of prevalence, causes, and risk factors.
- Summary of current treatment options.
Main Results:
- Iron deficiency anemia is the most common form, with stages including depleted iron stores, iron-deficient erythropoiesis, and overt anemia.
- Pregnancy anemia can be exacerbated by bleeding events and leads to risks like intrauterine growth retardation, prematurity, and increased need for blood transfusions.
- Therapeutic approaches include oral iron and intravenous iron preparations.
Conclusions:
- Anemia in pregnancy requires careful management due to significant risks.
- Prophylaxis and timely treatment with iron supplementation are crucial.
- Oral and intravenous iron are key therapeutic options for pregnancy anemia.
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