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The type I interferons: Basic concepts and clinical relevance in immune-mediated inflammatory diseases

Consuelo M López de Padilla1, Timothy B Niewold1

  • 1Division of Rheumatology and Department of Immunology, Mayo Clinic, Rochester, MN 55905, USA.

Gene
|September 28, 2015
PubMed
Summary

Type I interferons, crucial for antiviral defense, are explored for their complex biology and roles in autoimmune diseases. This review details their molecular mechanisms and therapeutic potential.

Keywords:
Autoimmune diseasesIdiopathic inflammatory myopathiesInterferon alphaInterferon betaInterferon signatureMultiple sclerosisRheumatoid arthritisSystemic lupus erythematosus

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