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ESTIMATING THE RISK OF CARDIO VASCULAR DISEASES AMONG PAKISTANI DIABETICS USING U.K. PDS RISK ENGINE
Insights
This study assessed coronary heart disease (CHD) risk in Pakistani diabetics using the UKPDS Risk Engine. Results indicate a lower CVD risk compared to Western populations, informing personalized treatment strategies.
Area of Science:
- Cardiology
- Endocrinology
- Public Health
Background:
- Coronary Heart Disease (CHD) risk estimation aids clinicians in identifying high-risk diabetic populations for effective treatment.
- Personalized CHD risk assessment is recommended for diabetic patients to prevent harm from aggressive risk factor modification.
- The UKPDS Risk Engine is a common tool for assessing cardiovascular disease (CVD) risk in diabetics, with limited data on Pakistani populations.
Purpose of the Study:
- To assess the risk of cardiovascular disease (CVD) among type-2 diabetic patients in Pakistan.
- To analyze CHD risk using the UKPDS Risk Engine in a Pakistani diabetic cohort.
Main Methods:
- A descriptive study analyzed data from 470 type-2 diabetic patients at Services Institute of Medical Sciences, Lahore.
- The UKPDS Risk Engine was utilized to calculate CHD risk for the study cohort.
Main Results:
- The 10-year risk for CHD was 9.4%, fatal CHD was 4.4%, stroke was 1.7%, and fatal stroke was 0.2%.
- Calculated risks were compared to findings from Western countries.
Conclusions:
- Pakistani diabetics exhibit a lower risk of CVD compared to their counterparts in Western countries.
- Findings suggest potential differences in CVD risk profiles between Pakistani and Western diabetic populations.
Background:
The concept of risk estimation of Coronary Heart Disease (CHD) is helpful for clinician to identifying high risk populations for their effective treatment. Latest studies recommended only initiating cardioprotective treatment in diabetic patients based on personalized CHD risk estimates so as to reduce undue harm from overly aggressive risk factor modification. The United Kingdom Prospective Diabetes Study (UK PDS) Risk Engine is a widely used tool to assess the risk of Cardio Vascular diseases (CVD) in diabetics. The literature search so far did not reveal any study of risk assessment among Pakistani Diabetics.
Methods:
This descriptive study is based on the data of 470 type-2 diabetics seen in Department of Endocrinology and Metabolism, Services Institute of Medical Sciences, Lahore during 2011. The data of these 470 patients was analyzed through UKPDS Risk Engine. CHD risk was calculated.
Results:
The 10 years risk of CHD, fatal CHD, stroke and fatal stroke was 9.4%, 4.4%, 1.7% and 0.2% respectively.
Conclusions:
The present study show a lower risk of CVD occurring among Pakistani diabetics as compared to studies from western countries.
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