Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Validation of a novel multi-luminance shape discrimination test for assessment of functional vision.

Documenta ophthalmologica. Advances in ophthalmology·2026
Same author

Safety and efficacy of MCO-010 optogenetic therapy in patients with Stargardt disease in USA (STARLIGHT): an open-label multi-center Ph2 trial.

EClinicalMedicine·2025
Same author

Response: Promise and open questions of optogenetic vision restoration by MCO.

Molecular therapy : the journal of the American Society of Gene Therapy·2025
Same author

A synthetic opsin restores vision in patients with severe retinal degeneration.

Molecular therapy : the journal of the American Society of Gene Therapy·2025
Same author

Monitoring Visual Cortical Activities During Progressive Retinal Degeneration Using Functional Bioluminescence Imaging.

Frontiers in neuroscience·2021
Same author

Biodistribution of adeno-associated virus type 2 carrying multi-characteristic opsin in dogs following intravitreal injection.

Journal of cellular and molecular medicine·2021
Same journal

Fluorescence and diffuse reflectance provide similar accuracy in recovering fluorophore concentration at short source-detector separations.

Journal of modern optics·2022
Same journal

A holographic waveguide based eye tracking device.

Journal of modern optics·2020
Same journal

Smartphone-based imaging of the corneal endothelium at sub-cellular resolution.

Journal of modern optics·2017
Same journal

Enhancement of intrinsic optical signal recording with split spectrum optical coherence tomography.

Journal of modern optics·2017
Same journal

High visibility in two-color above-threshold photoemission from tungsten nanotips in a coherent control scheme.

Journal of modern optics·2017
Same journal

Quantum memory receiver for superadditive communication using binary coherent states.

Journal of modern optics·2016
See all related articles

Related Experiment Video

Updated: Apr 2, 2026

In vivo Optogenetic Stimulation of the Rodent Central Nervous System
09:37

In vivo Optogenetic Stimulation of the Rodent Central Nervous System

Published on: January 15, 2015

61.0K

Optical Techniques in Optogenetics.

Samarendra K Mohanty1, Vasudevan Lakshminarayananan2

  • 1Biophysics and Physiology Group, Department of Physics, The University of Texas at Arlington, USA. Tel. 817-272-1177.

Journal of Modern Optics
|September 29, 2015
PubMed
Summary
This summary is machine-generated.

Optogenetics uses light to control cells, revolutionizing neuroscience and cell biology. This technique enables precise control over gene expression and cellular activities for research and medical applications.

Keywords:
Optogeneticsbiomedical opticsbiophotonicsbiophysicscell biologyneurosciencevision science

More Related Videos

Laser-scanning Photostimulation of Optogenetically Targeted Forebrain Circuits
07:43

Laser-scanning Photostimulation of Optogenetically Targeted Forebrain Circuits

Published on: December 27, 2013

9.8K
Optogenetic Manipulation of Neuronal Activity to Modulate Behavior in Freely Moving Mice
14:40

Optogenetic Manipulation of Neuronal Activity to Modulate Behavior in Freely Moving Mice

Published on: October 27, 2020

20.4K

Related Experiment Videos

Last Updated: Apr 2, 2026

In vivo Optogenetic Stimulation of the Rodent Central Nervous System
09:37

In vivo Optogenetic Stimulation of the Rodent Central Nervous System

Published on: January 15, 2015

61.0K
Laser-scanning Photostimulation of Optogenetically Targeted Forebrain Circuits
07:43

Laser-scanning Photostimulation of Optogenetically Targeted Forebrain Circuits

Published on: December 27, 2013

9.8K
Optogenetic Manipulation of Neuronal Activity to Modulate Behavior in Freely Moving Mice
14:40

Optogenetic Manipulation of Neuronal Activity to Modulate Behavior in Freely Moving Mice

Published on: October 27, 2020

20.4K

Area of Science:

  • Neuroscience
  • Cell Biology
  • Biomedical Research

Background:

  • Optogenetics has rapidly advanced neuroscience and cell biology.
  • It offers a powerful paradigm for basic and applied research.

Purpose of the Study:

  • To review fundamental optogenetics concepts.
  • To highlight key biological and biomedical applications.
  • To emphasize advancements in light-based control methods.

Main Methods:

  • Review of optogenetics principles.
  • Analysis of biological and biomedical applications.
  • Focus on light-based methods for gene expression control, spatial stimulation, and activity detection.

Main Results:

  • Optogenetics provides precise optical control of cellular functions.
  • Diverse applications span basic research to medical contexts.
  • Advancements include sophisticated gene expression modulation and activity monitoring.

Conclusions:

  • Optogenetics is a transformative tool in modern biological and medical research.
  • Its applications continue to expand, offering new avenues for investigation and therapy.