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QM/MM Studies Reveal How Substrate-Substrate and Enzyme-Substrate Interactions Modulate Retaining

Hansel Gómez1, Fernanda Mendoza1, José M Lluch1

  • 1Institut de Biotecnologia i de Biomedicina (IBB), Universitat Autònoma de Barcelona, Bellaterra (Barcelona), Spain; Departament de Química, Universitat Autònoma de Barcelona, Bellaterra (Barcelona), Spain.

Advances in Protein Chemistry and Structural Biology
|September 30, 2015
PubMed

Keywords:
Double-displacement mechanismFront-side attackQM/MMRetaining glycosyltransferasesSubstrate-assisted catalysis

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