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Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
Published on: April 18, 2025
Trends in Biotechnological Drugs for Cancer Treatment
Natalia L von Ranke, Iolanda M Fierro1, Adelaide M S Antunes
1National Institute of Industrial Property, Rio de Janeiro, Brazil. ifierro@inpi.gov.br.
Background:
Biotechnology, which promoted revolutions in many fields, generates great expectations for the future, mainly in the pharmaceutical sector for the treatment of several diseases. Cancer is a leading cause of death worldwide and due to its complexity and singularity, there are a number of challenges that limit the development of new drugs for antitumor therapies, making the research for cancer treatment one of the most exploited in the medical field.
Objective:
The main objective of this article is to identify trends of biotechnological advances that may have application in improving cancer therapies.
Method:
Information from patent applications of biotechnological drugs in the last five years was retrieved using Thomson Reuters Integrity database.
Results:
Cancer is the leading therapeutic condition found in patent documents. The subject matter most cited in patent applications includes monoclonal antibodies, adoptive cell therapy, RNA interference and new vaccine peptides.
Conclusion:
The analysis of the documents has provided an overview of new biological alternatives for use in cancer treatment, showing potential avenues for years to come.
Insights
Biotechnology offers new avenues for cancer treatment. Patent analysis reveals key advances in monoclonal antibodies, cell therapy, RNA interference, and vaccines, paving the way for future antitumor therapies.
Area of Science:
- Biotechnology
- Oncology
- Pharmaceutical Sciences
Background:
- Biotechnology drives innovation in pharmaceuticals, particularly for treating complex diseases like cancer.
- Cancer remains a leading cause of death, presenting significant challenges in developing effective antitumor therapies.
Purpose of the Study:
- To identify emerging biotechnological trends with potential applications in enhancing cancer therapies.
- To analyze recent patent filings for insights into novel cancer treatment strategies.
Main Methods:
- Retrieved data from patent applications filed within the last five years.
- Utilized the Thomson Reuters Integrity database for comprehensive information retrieval.
Main Results:
- Cancer emerged as the most frequent therapeutic area in patent documents.
- Key areas of innovation include monoclonal antibodies, adoptive cell therapy, RNA interference, and novel vaccine peptides.
Conclusions:
- Patent analysis provides an overview of novel biological approaches for cancer treatment.
- These findings highlight promising future directions for the development of advanced antitumor therapies.
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