Related Experiment Video
Updated: Apr 1, 2026

Low-cost Custom Fabrication and Mode-locked Operation of an All-normal-dispersion Femtosecond Fiber Laser for Multiphoton Microscopy
Published on: November 22, 2019
Multimodal fiber source for nonlinear microscopy based on a dissipative soliton laser
1School of Applied and Engineering Physics, Cornell University, Ithaca, New York 14853, USA.
We demonstrate spectral compression of femtosecond fiber lasers to generate picosecond pulses for Raman microscopy. This creates a versatile multimodal platform for advanced nonlinear microscopy techniques.
Area of Science:
- Optics and Photonics
- Biomedical Imaging
- Laser Physics
Background:
- High-energy femtosecond fiber lasers are cost-effective for multiphoton-fluorescence and harmonic-generation imaging.
- Picosecond pulses are optimal for Raman scattering microscopy, necessitating a source offering both pulse durations for multimodal nonlinear microscopy.
Purpose of the Study:
- To develop a robust fiber laser source capable of generating synchronized picosecond pulse trains for Raman scattering microscopy.
- To adapt existing femtosecond fiber laser technology for multimodal nonlinear microscopy applications.
Main Methods:
- Spectral compression of a high-power femtosecond fiber laser to produce transform-limited picosecond pulses.
- Utilizing these picosecond pulses to pump a fiber optical parametric oscillator (FOPO).
Main Results:
- Successfully generated transform-limited picosecond pulses via spectral compression.
- Developed a robust fiber source delivering synchronized picosecond pulse trains.
- Demonstrated a viable route to a multimodal nonlinear microscopy platform.
Conclusions:
- Spectral compression of femtosecond fiber lasers provides a method for generating picosecond pulses.
- The developed fiber source is suitable for Raman scattering microscopy.
- This system enables multimodal nonlinear microscopy by combining different imaging techniques.
More Related Videos
14:18Automation of Mode Locking in a Nonlinear Polarization Rotation Fiber Laser through Output Polarization Measurements
Published on: February 28, 2016
08:49Author Spotlight: Unveiling the Potential of VSFG Microscopy in Studying Mesoscopically Heterogeneous Self-Assembled Structures
Published on: December 1, 2023