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Breast milk composition and infant nutrient intakes during the first 12 months of life
V Grote1, E Verduci2, S Scaglioni2
1Division Metabolic and Nutritional Medicine, Dr von Hauner Children's Hospital, University of Munich, Medical Centre, Munich, Germany.
Insights
This study quantified human milk intake and nutrient composition in infants up to 12 months. Findings offer reference ranges for breastfed infants and guidance for infant nutrition.
Area of Science:
- Pediatrics
- Human Lactation
- Infant Nutrition
Background:
- Human milk is crucial for infant nutrition.
- Understanding milk supply and composition is vital for infant health.
- Variations in human milk can impact infant growth and development.
Purpose of the Study:
- To quantify human milk supply and intake in breastfed infants up to 12 months.
- To analyze human milk composition, including macronutrients and fatty acids.
- To establish reference ranges for nutrient intake in exclusively breastfed infants.
Main Methods:
- 174 Italian infants were monitored from birth to 12 months using test-weighing and 3-day food records.
- Breast milk samples from 30 mothers were analyzed for protein, carbohydrates, lipids, and fatty acids at specific time points.
- Data collection included infant milk intake and maternal characteristics.
Main Results:
- Human milk intake varied, decreasing from 625 ml/day at 1 month to 477 ml/day at 6 months.
- Energy and protein intake increased significantly from 1 to 12 months.
- Galactose, non-protein nitrogen, and protein content decreased from 1 to 6 months; maternal factors influenced fatty acid levels.
Conclusions:
- The study provides reference ranges for nutrient intake in breastfed infants.
- These findings can inform guidelines for infant feeding, especially for those not fully breastfed.
- Understanding human milk dynamics supports optimal infant nutrition strategies.
Background/Objectives:
The objective of this study was to quantify human milk supply and intake of breastfed infants up to age 12 months. In addition, human milk composition was quantified per energetic macronutrient and fatty-acid composition in a subsample of lactating mothers.
Subjects/Methods:
One hundred and seventy-four Italian breastfed children were followed using test-weighing and 3-day food protocols from birth to age 12 months. From a subsample of 30 mothers breast milk samples were collected at child ages one (T1), two (T2), three (T3) and six (T6) months, and were analyzed for the amount of protein, digestible carbohydrates, total lipids and fatty-acid composition.
Results:
One hundred and forty-two (82%) filled in at least one 3-day food protocol within the first 12 months of life and complied with test-weighing of all milk feeds. The number of valid food protocols declined from 126 infants at 1 month to 77 at 12 months of age. Only galactose, non-protein nitrogen and protein decreased significantly from age 1 to age 6 months of lactation. Maternal body mass index and age affected fatty-acid levels in human milk. Median human milk intake decreased from 625 ml at T1, over 724 ml at T3 to 477 ml/day at T6. Average energy and %energy from protein intake per day increased from 419 kcal (s.d. 99) and 8.4% (1.0) at T1, respectively, to 860 kcal (145) and 16.1% (2.6) at T12.
Conclusions:
These data provide a reference range of nutrient intakes in breastfed infants and may provide guidance for defining optimal nutrient intakes for infants that cannot be fully breastfed.
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