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Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
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Cochlear involvement in patients with ulcerative colitis.

M Sagit1, S Guler2, A Karaman3

  • 1Department of ENT,Kayseri Training and Research Hospital,Turkey.

The Journal of Laryngology and Otology
|October 1, 2015
PubMed
Summary
This summary is machine-generated.

Ulcerative colitis patients show cochlear involvement, indicated by reduced otoacoustic emissions, even with normal hearing thresholds. This suggests hearing issues may be an extraintestinal manifestation of the disease.

Keywords:
CochleaHearing LossInflammatory Bowel DiseasesOtoacoustic EmissionsSpontaneousUlcerative Colitis

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Area of Science:

  • Otolaryngology
  • Gastroenterology
  • Audiology

Background:

  • Ulcerative colitis (UC) is a chronic inflammatory bowel disease.
  • Extraintestinal manifestations (EIMs) are common in UC patients.
  • Cochlear involvement as an EIM in UC requires further investigation.

Purpose of the Study:

  • To determine if cochlear dysfunction is an extraintestinal manifestation in patients with ulcerative colitis.
  • To compare audiological findings between UC patients and healthy controls.

Main Methods:

  • Included 44 UC patients and 44 age-matched healthy controls.
  • Performed pure tone audiometry, speech audiometry, and distortion product otoacoustic emission (DPOAE) tests.
  • Analyzed audiometric results and correlated them with UC disease activity.

Main Results:

  • UC patients exhibited significantly higher pure tone threshold averages compared to controls (p < 0.05).
  • DPOAE measurements indicated reduced amplitude in UC patients, suggesting subclinical cochlear dysfunction.
  • No significant correlation was found between hearing thresholds and UC disease activity.

Conclusions:

  • Cochlear involvement, evidenced by decreased DPOAE amplitudes, is present in UC patients.
  • This subclinical cochlear dysfunction may represent an extraintestinal manifestation of ulcerative colitis.
  • Audiological monitoring, including DPOAE, could be beneficial for UC patients.