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Choroid plexus papilloma in early infants.
H Kawano1, M Hayashi, H Kobayashi
1Department of Neurosurgery, Fukui Medical School, Japan.
Zentralblatt Fur Neurochirurgie
|January 1, 1989
Summary
Successful surgical treatment for choroid plexus papillomas in infants is highlighted. Early diagnosis and intervention are crucial for managing increased intracranial pressure and hydrocephalus, leading to positive developmental outcomes.
Area of Science:
- Pediatric Neurosurgery
- Neuro-oncology
- Developmental Pediatrics
Background:
- Choroid plexus papillomas are rare tumors often presenting in infancy.
- These tumors can lead to hydrocephalus due to cerebrospinal fluid (CSF) overproduction or obstruction.
Observation:
- Four infants presented with symptoms of increased intracranial pressure and hydrocephalus within 8 weeks of birth.
- Tumors were located in the lateral ventricles, with three being benign and one malignant choroid plexus papilloma.
- Computerized tomography (CT) scans were instrumental in diagnosing both the tumors and associated hydrocephalus.
Findings:
- Surgical resection was the primary treatment, achieving successful outcomes in all four cases.
- Angiography revealed tumor staining in two patients, aiding in surgical planning.
- Three infants demonstrated normal physical and mental development post-surgery.
Implications:
- Early diagnosis and surgical management of choroid plexus papillomas are vital for preventing severe neurological deficits.
- Prompt treatment of hydrocephalus associated with these tumors is critical for favorable neurodevelopmental trajectories.
- This case series underscores the efficacy of surgical intervention in pediatric choroid plexus papilloma management.