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Obesity: a key component of psoriasis.
Bernardo Correia1, Tiago Torres
1Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Portugal. bernardo_correia_@hotmail.com.
Acta Bio-Medica : Atenei Parmensis
|October 1, 2015
Summary
Psoriasis is linked to obesity, increasing cardiovascular risks. Managing weight is crucial for effective psoriasis treatment and patient outcomes.
Area of Science:
- Dermatology and Cardiology
- Metabolic Syndrome Research
Background:
- Psoriasis is associated with cardiometabolic comorbidities and increased cardiovascular disease (CVD) risk.
- Obesity plays a significant role in linking psoriasis and CVD, supported by growing epidemiological evidence.
Purpose of the Study:
- To review the association between psoriasis and obesity.
- To explore the physiopathological mechanisms linking these conditions.
- To emphasize the importance of obesity control in psoriasis management and systemic treatment efficacy/safety.
Main Methods:
- Systematic review of current evidence.
- Analysis of physiopathological mechanisms.
- Synthesis of data on obesity's impact on psoriasis treatment.
Main Results:
- Obesity is a major factor in psoriatic patients, affecting treatment efficacy and safety.
- Weight loss positively impacts psoriasis severity and treatment response.
- Chronic inflammation from obesity is a key component of the psoriasis-obesity link.
Conclusions:
- The association between psoriasis and obesity is multifactorial, involving genetic, environmental, and immune factors.
- Obesity management is essential for psoriatic patients, influencing treatment outcomes.
- Clinicians must recognize this link to provide appropriate multidisciplinary care and follow-up.
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