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Related Experiment Videos

Pancreatic cystic neoplasms.

D Mathieu1, B Guigui, P J Valette

  • 1Département de Radiologie, Hôpital Henri Mondor, Créteil, France.

Radiologic Clinics of North America
|January 1, 1989
PubMed
Summary

Cystic pancreatic neoplasms are increasingly detected. Imaging can distinguish some types, but fine needle aspiration is often needed for definitive diagnosis and malignancy assessment.

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Area of Science:

  • Gastroenterology
  • Oncology
  • Radiology

Background:

  • Cystic neoplasms of the pancreas are uncommon but increasingly diagnosed due to advanced imaging.
  • Recent discoveries have introduced new pathological entities with distinct prognoses.
  • Distinguishing between microcystic and mucinous adenomas is often possible with imaging.

Purpose of the Study:

  • To review the diagnostic capabilities of imaging modalities for pancreatic cystic neoplasms.
  • To highlight the limitations of current imaging in differentiating malignancy.
  • To emphasize the role of fine needle aspiration in diagnosis.

Main Methods:

  • Review of imaging features (sonography, CT) of pancreatic cystic neoplasms.
  • Correlation of imaging findings with pathological diagnoses.

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  • Discussion of diagnostic algorithms including fine needle aspiration.

    • Main Results:

    • Imaging can differentiate microcystic adenoma (honeycomb appearance) from mucinous cystadenoma (multilocular, papillary projections).
    • Sonography and CT cannot reliably differentiate mucinous cystadenoma from cystadenocarcinoma; malignancy grade influences imaging features.
    • Fine needle aspiration with stains is recommended for definitive diagnosis in most cases.

    Conclusions:

    • While imaging aids in classifying some pancreatic cystic neoplasms, it has limitations in detecting malignancy.
    • Fine needle aspiration remains a crucial tool for accurate diagnosis and management planning.
    • Further research may improve noninvasive differentiation of malignant potential.