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Primary meningeal small lymphocytic lymphoma
1Department of Pathology, University of Southern California, Los Angeles 90033.
The American Journal of Surgical Pathology
|January 1, 1989
Summary
This study details a rare case of primary meningeal small lymphocytic lymphoma (SLL) in the brain. The lymphoma appeared as a single, large mass and showed a unique pseudofollicular pattern on histology.
Area of Science:
- Neurology
- Oncology
- Hematology
Background:
- Primary meningeal lymphoma is rare.
- Small lymphocytic lymphoma (SLL) typically affects lymph nodes but can involve the central nervous system.
Observation:
- A solitary large extraaxial mass lesion was identified.
- Histological examination revealed a prominent pseudofollicular pattern.
Findings:
- The mass was diagnosed as primary meningeal SLL.
- Noninvasive staging procedures ruled out extracranial lymphoma.
- Bone marrow and peripheral blood analyses were negative for lymphoma.
Implications:
- This case expands the spectrum of CNS lymphoma presentations.
- Highlights the importance of considering SLL in the differential diagnosis of dural masses.
- Suggests that primary meningeal SLL can present without systemic involvement.