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Updated: Apr 1, 2026

Microdialysis of Excitatory Amino Acids During EEG Recordings in Freely Moving Rats

Microdialysis of Excitatory Amino Acids During EEG Recordings in Freely Moving Rats

Published on: November 8, 2018

Noncirrhotic hyperammonemia causing relapsing altered mental status.

Chibuzo Clement Odigwe¹, Binod Khatiwada¹, Christopher Holbrook¹

¹Department of Medicine, St. Joseph Hospital, 2900 North Lake Shore Drive, Chicago, Illinois. Dr. Upadhyay is currently with the Department of Medicine, University of Nevada, Reno.

Proceedings (Baylor University. Medical Center)

|October 2, 2015

Summary

This summary is machine-generated.

Noncirrhotic hyperammonemia, a condition causing brain dysfunction, is increasingly recognized. This case highlights a patient with relapsing altered mental status diagnosed with this disorder.

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Area of Science:

Neurology
Hepatology
Internal Medicine

Background:

Hyperammonemia is a known cause of encephalopathy, typically associated with liver disease.
The clinical significance of noncirrhotic hyperammonemia is gaining increasing recognition in medical literature.

Observation:

A male patient presented with recurrent episodes of altered mental status.
Initial assessments were conducted at our hospital for the presenting symptoms.

Findings:

The patient was diagnosed with noncirrhotic hyperammonemia.
This diagnosis explains the relapsing neurological symptoms observed.

Implications:

This case underscores the importance of considering noncirrhotic hyperammonemia in patients with unexplained encephalopathy.
Further research into the mechanisms and management of noncirrhotic hyperammonemia is warranted.