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Spatial Moran Models I. Stochastic Tunneling in the Neutral Case
Richard Durrett1, Stephen Moseley1
1Department of Mathematics, Box 90320, Duke U., Durham NC 27708-0320.
Abstract:
We consider a multistage cancer model in which cells are arranged in a d-dimensional integer lattice. Starting with all wild-type cells, we prove results about the distribution of the first time when two neutral mutations have accumulated in some cell in dimensions d ≥ 2, extending work done by Komarova [12] for d = 1.
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