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Cardiac Rehabilitation Improves the QRS Fragmentation in Patients With ST Elevatıon Myocardial Infarction

Mustafa Bulut1, Rezzan Deniz Acar1, Sunay Ergün2

  • 1Department of Cardiology, Kartal Kosuyolu Education and Research Hospital, Istanbul, Turkey.

Journal of Cardiovascular and Thoracic Research
|October 3, 2015
PubMed

Insights

Exercise-based cardiac rehabilitation significantly reduces fragmented QRS (fQRS) in ST-elevation myocardial infarction (STEMI) patients. This improvement in myocardial electrical stability may enhance survival and reduce cardiac events, particularly in hypertensive individuals.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Preventive Cardiology

Background:

  • Fragmented QRS (fQRS) is an electrocardiogram (ECG) finding associated with adverse cardiac outcomes.
  • ST-elevation myocardial infarction (STEMI) is a critical condition requiring effective management strategies.
  • Cardiac rehabilitation (CR) is a key component of post-MI care.

Purpose of the Study:

  • To evaluate the impact of exercise-based cardiac rehabilitation (CR) on fragmented QRS (fQRS) in patients with ST-elevation myocardial infarction (STEMI).
  • To assess whether CR influences the presence and persistence of fQRS on ECG.
  • To explore potential correlations between fQRS changes and patient characteristics.

Main Methods:

  • A study involving 97 STEMI patients undergoing CR and 81 control patients.
  • ECGs were analyzed before and after CR to identify fragmented QRS (fQRS).
  • Patients were categorized into transient and persistent fQRS groups based on ECG findings post-CR.

Main Results:

  • A significant reduction in fQRS was observed in the CR group compared to the control group (P = .034).
  • Among CR patients, fQRS decreased, with 35 showing persistent fQRS and 17 showing transient fQRS.
  • Hypertension was the only characteristic significantly correlated with fQRS changes.

Conclusions:

  • Exercise-based CR effectively decreases fragmented QRS (fQRS) in STEMI patients.
  • The reduction in fQRS suggests improved myocardial electrical stability.
  • CR may serve as a predictor of increased survival and reduced major cardiac events, especially in hypertensive STEMI patients.
Abstract

Keywords:
Cardiac RehabilitationHypertensionMyocardial Electrical StabilityQRS Fragmentation

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