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Related Experiment Video

Updated: Apr 1, 2026

Proximal Cadaveric Femur Preparation for Fracture Strength Testing and Quantitative CT-based Finite Element Analysis

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Published on: March 11, 2017

A technique for developing CAD geometry of long bones using clinical CT data.

Matthew L Davis¹, Nicholas A Vavalle¹, Joel D Stitzel¹

¹Virginia Tech-Wake Forest University School of Biomedical Engineering and Sciences, Winston-Salem, NC, USA; Wake Forest University School of Medicine, Winston-Salem, NC, USA.

Medical Engineering & Physics

|October 4, 2015

Summary

This study introduces a method to create 3D bone models from CT scans, accurately measuring cortical thickness for computational modeling and orthopedic implant design.

Keywords:

Area moment of inertia Biomechanics CAD Cortical thickness Full width half max Subject specific bone model

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Area of Science:

Biomedical Engineering
Medical Imaging
Orthopedics

Background:

Computed tomography (CT) scans are crucial for creating computational bone models.
Accurate characterization of bone geometry, particularly cortical thickness, is essential for biomechanical analysis.

Purpose of the Study:

To present a method for generating CAD representations of long bones from clinical CT scans.
To apply this method to six long bones and validate the accuracy of cortical thickness measurements.

Main Methods:

Segmentation of periosteal and endosteal bone surfaces from CT data.
Calculation of characteristic cortical thickness (Tc) along the bone axis.
Imputation of endosteal bone data in regions below scanner threshold using literature values.

Main Results:

Successfully generated CAD models from CT scans, with 74.7% of geometry derived from scan data on average.
Cortical thickness was predicted with a 3.1% error compared to experimental measurements of cadaveric bone.
The method effectively characterized cortical thickness along the bone length.

Conclusions:

The developed method provides a viable solution for characterizing bone thickness from CT scans.
This approach can aid in the development of subject-specific finite element models and orthopedic implant designs.