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Missing diagnosis: gingival hypertrophy due to amlodipine
1Senior Resident, Department of Medicine, University College of Medical Sciences & Guru Teg Bahadur Hospital (University of Delhi), Delhi110095, India.
Indian Heart Journal
|October 4, 2015
Summary
Gingival hypertrophy, a gum overgrowth condition, can be a side effect of certain medications. This case highlights Amlodipine-induced gum hypertrophy, which resolved after drug cessation.
Area of Science:
- Cardiology
- Pharmacology
- Oral Medicine
Background:
- Gingival hypertrophy (GH) is a multifactorial condition linked to inflammation, pregnancy, nutritional deficiencies, systemic diseases, and drug use.
- Calcium channel blockers (CCBs) are among the medications associated with drug-induced gingival overgrowth.
- Early identification and management are crucial for patient outcomes.
Observation:
- A 45-year-old woman developed gum hypertrophy after 1.5 years of daily Amlodipine (10mg) and Atenelol (50mg) use.
- The gingival overgrowth was visually documented in a pictorial case presentation.
- The patient's medical history and medication regimen were thoroughly reviewed.
Findings:
- Discontinuation of Amlodipine led to the complete reversal of gingival hypertrophy.
- Amlodipine, a commonly prescribed CCB, was identified as the likely causative agent.
- This case reinforces the association between Amlodipine and drug-induced gingival hypertrophy.
Implications:
- Physicians should maintain a high index of suspicion for drug-induced gingival hypertrophy in patients on CCBs.
- Reviewing and potentially modifying medication regimens can effectively manage this adverse effect.
- Pictorial case reports can enhance clinical awareness and diagnostic capabilities for rare drug side effects.
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