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Updated: Apr 1, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
Multiple intra-renal artery aneurysms causing renal obstruction managed with radical nephrectomy
Jason Frankel1, Gregory Murphy, Peter Haddock
1Urology Division, Hartford Healthcare Medical Group, Hartford, Connecticut, USA.
Multiple large renal artery aneurysms caused kidney obstruction and damage in a hypertensive male. Surgical removal of the non-functioning right kidney (radical nephrectomy) was successful, preserving patient health.
Area of Science:
- Vascular Surgery
- Nephrology
- Radiology
Background:
- Hypertension is a common condition that can affect various organs.
- Renal artery aneurysms are rare vascular abnormalities.
- Intra-renal aneurysms can lead to significant renal complications.
Observation:
- A 46-year-old male with hypertension presented with abdominal fullness and a palpable mass.
- Computed tomographic angiography revealed multiple large intra-renal aneurysms.
- The aneurysms caused obstruction of the renal calyces, leading to hydronephrosis and minimal parenchyma.
Findings:
- The renal deterioration was attributed to obstruction by large intra-renal aneurysms.
- The right kidney was non-functional due to the aneurysm-induced damage.
- An open radical nephrectomy was performed successfully.
Implications:
- This case highlights a rare cause of kidney deterioration and obstruction.
- Early diagnosis of intra-renal aneurysms is crucial for effective management.
- Radical nephrectomy can be a viable treatment option for non-functioning kidneys with complex aneurysmal disease.
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