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Updated: Apr 1, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
Multiple intra-renal artery aneurysms causing renal obstruction managed with radical nephrectomy
Jason Frankel1, Gregory Murphy, Peter Haddock
1Urology Division, Hartford Healthcare Medical Group, Hartford, Connecticut, USA.
Abstract:
A 46-year-old male with a history of hypertension presented with symptoms of persistent abdominal fullness and a non-pulsatile abdominal mass. Subsequent computed tomographic angiography studies revealed the presence multiple large renal aneurysms from the segmental branches of the renal artery and an enlarged hydronephrotic kidney with minimal parenchyma. The renal deterioration appeared to be as a result of an obstruction caused by the large intra-renal aneurysms at the level of the renal calyces. Since the right kidney had no function, an open radical nephrectomy was subsequently performed without complications at 3 months follow up.
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