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Enhancing vaccine safety capacity globally: A lifecycle perspective.
Robert T Chen1, Tom T Shimabukuro1, David B Martin2
1Office of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Vaccine
|October 5, 2015
Summary
Vaccine safety controversies are likely to continue. Improving vaccine safety capacity through lifecycle approaches can mitigate future controversies in developed and developing nations.
Area of Science:
- Public Health
- Immunization
- Epidemiology
Background:
- Vaccine safety controversies have emerged globally since the late 20th century.
- Maturing national immunization programs highlight adverse events, both true reactions and coincidental events.
- Anticipated increase in vaccine safety controversies necessitates proactive strategies.
Purpose of the Study:
- To examine pre- and post-licensure opportunities for enhancing vaccine safety.
- To adopt a comprehensive "lifecycle" approach to vaccine safety.
- To address vaccine safety in both developed (U.S., Europe) and low- and middle-income countries.
Main Methods:
- Review of potential vaccine safety improvements.
- Lifecycle analysis of vaccine safety considerations.
- Comparative examination of strategies in different economic contexts.
Main Results:
- Identified opportunities for improving vaccine safety capacity.
- Proposed a lifecycle framework for vaccine safety management.
- Highlighted the need for tailored approaches in diverse healthcare settings.
Conclusions:
- Proactive enhancement of vaccine safety capacity is crucial.
- A lifecycle approach offers a robust framework for managing vaccine safety.
- Continuous improvement is essential to address evolving challenges in immunization programs.
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