Recent advances in amino acid analysis by capillary electromigration methods, 2013-2015

Area of Science:

• Analytical Chemistry
• Biochemistry

Background:

• Capillary electrophoresis (CE) is a powerful separation technique.
• Amino acid analysis is crucial in various scientific fields.

Purpose of the Study:

• To review significant research on amino acid analysis using CE between June 2013 and May 2015.
• To highlight new developments in detection and injection methods.
• To survey applications in neurochemistry, clinical diagnostics, metabolomics, food, and agriculture.

Main Methods:

• Literature review of research articles published on amino acid analysis by CE.
• Categorization of studies based on methodological advancements and application areas.

Main Results:

• Key developments include enhanced detection techniques and improved injection methods for CE-based amino acid analysis.
• Significant progress was observed in enantiomeric separation.
• A notable increase in publications focused on metabolomic studies using CE for amino acid analysis.

Conclusions:

• CE continues to be a vital tool for amino acid analysis, with ongoing innovation in separation and detection.
• The expanding applications in metabolomics and food science underscore the technique's versatility and importance.