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Subcorneal pustular dermatosis associated with Coccidioides immitis
Sanjana Iyengar, Cindy J Chambers, Shurong Chang
1University of California, Davis. vrs2001@gmail.com.
Dermatology Online Journal
|October 6, 2015
Summary
Coccidioidomycosis, a fungal lung infection, can cause skin issues like subcorneal pustular dermatosis. This case highlights a link between Valley fever and this specific skin condition, suggesting further research is needed.
Area of Science:
- Mycology
- Dermatology
- Infectious Diseases
Background:
- Coccidioidomycosis, or Valley fever, is a primary pulmonary infection caused by airborne spores of Coccidioides immitis.
- Reactive skin eruptions secondary to pulmonary Coccidioidomycosis are diagnostically challenging due to the absence of the organism in skin biopsies.
Purpose of the Study:
- To present a unique case of subcorneal pustular dermatosis as a manifestation of primary pulmonary Coccidioidomycosis.
- To highlight the diagnostic difficulties and potential association between these two conditions.
Main Methods:
- Case report of an adolescent male with Coccidioidomycosis.
- Biopsy-proven subcorneal pustular dermatosis.
- Serological testing for Coccidioidomycosis.
- Monitoring of symptoms and response to antifungal therapy.
Main Results:
- The patient presented with biopsy-proven subcorneal pustular dermatosis.
- Serological studies confirmed increasing titers for Coccidioidomycosis.
- Symptoms resolved promptly after initiating systemic antifungal treatment.
Conclusions:
- Subcorneal pustular dermatosis can be a reactive cutaneous eruption associated with primary pulmonary Coccidioidomycosis.
- This case suggests a potential link between Valley fever and subcorneal pustular dermatosis that warrants further investigation.
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