Pitted keratolysis: successful management with mupirocin 2% ointment monotherapy

Pitted keratolysis is a benign dermatosis that occurs on plantar skin.

We describe a man with pitted keratolysis that was successfully treated with mupirocin 2% ointment monotherapy.

We reviewed PubMed for the following terms: mupirocin, ointment, pitted keratolysis, treatment. We also reviewed papers containing these terms and their references.

Complete resolution of pitted keratolysis occurred following monotherapy with twice daily application of mupirocin 2% ointment for a duration of three weeks. There was no recurrence at a follow-up visit eight weeks later.

Several topical and oral treatments are available to successfully manage pitted keratolysis. Our patient confirms previous reports of pitted keratolysis resolving with mupirocin 2% ointment treatment. Monotherapy with mupirocin 2% ointment should be considered as a primary treatment alternative for pitted keratolysis.