A case of Listeria monocytogenes endophthalmitis with recurrent inflammation and novel management

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Adam C Weber1, Ashleigh L Levison2, Sunil K Srivastava3

  • 1Cole Eye Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Mail Code i-32, Cleveland, OH, 44195, USA. webera2@ccf.org.

Journal of Ophthalmic Inflammation and Infection
|October 7, 2015
PubMed
Abstract

Insights

Listeria endophthalmitis, a rare infection, can lead to poor vision. Prompt diagnosis and aggressive treatment, including antibiotics and inflammation management, are crucial for visual recovery in these challenging cases.

Area of Science:

  • Ophthalmology
  • Infectious Diseases

Background:

  • Listeria monocytogenes is an uncommon cause of endogenous endophthalmitis.
  • Previous cases of Listeria endophthalmitis report poor visual acuity outcomes.

Purpose of the Study:

  • To report a case of Listeria endophthalmitis with recurrent inflammation.
  • To highlight treatment strategies and outcomes for this rare condition.

Main Methods:

  • A case report detailing the clinical course of Listeria endophthalmitis.
  • Treatment involved intravitreal and systemic antibiotics, and anterior chamber washout.

Main Results:

  • The patient experienced recurrent inflammation despite initial treatment.
  • Successful visual acuity recovery to 20/20 was achieved after anterior chamber washout.
  • Listeria species demonstrate low sensitivity to standard empiric antibiotic regimens.

Conclusions:

  • Early consideration of Listeria monocytogenes in endophthalmitis is vital due to its resistance to common therapies.
  • Aggressive management of inflammation is critical for favorable visual outcomes in infectious endophthalmitis.
Keywords:
Anterior chamber washoutBacterial endophthalmitisListeria monocytogenesRecurrent inflammation

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