Cholesterol granuloma: a case series & review of literature
Neha Shrirao1, Bipasha Mukherjee2, S Krishnakumar3
1Orbit, Oculoplasty, Reconstructive & Aesthetic Services, Sankara Nethralaya, Medical Research Foundation, 18, College Road, Chennai, 600 006, India.
Background:
Cholesterol granuloma (CG) is a foreign body reaction to crystallized cholesterol. Orbitofrontal CG is a rare entity with few cases reported in literature. It is usually seen in young to middle-aged males with a history of trauma. Computed tomography features include hypodense lesion-causing bone erosion. CG has typical histopathological features with cholesterol clefts, multinucleated giant cells, histiocytes, foamy macrophages, and altered blood pigments. Management is by total excision of the lesion with curettage of the underlying bone to prevent recurrence.
Material & Method:
We present an interventional case series of five patients of orbitofrontal CG, two of them females.
Result:
None of the patients gave a history of trauma. Management was by excision of the lesion and curettage confirmed with a 30° rigid endoscope.
Conclusion:
Cholesterol granulomas can present as superior orbital mass lesions in the absence of trauma.
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