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Viral hepatitis: A new HCV cell culture model for the next clinical challenges
Che C Colpitts1, Thomas F Baumert1
1Inserm, U1110, Institut de Recherche sur les Maladies Virales et Hépatiques, Université de Strasbourg, 67000 Strasbourg, France.
Nature Reviews. Gastroenterology & Hepatology
|October 7, 2015
Abstract:
Despite advances in hepatitis C treatment, substantial clinical hurdles remain to achieve universal cure and global control of infection. Saeed et al. identified SEC14L2 as a host factor permitting replication of clinical HCV isolates in cell culture, providing a novel system to model infection of patient-derived viruses.
