Related Experiment Video
Updated: Apr 1, 2026

Preparation and Characterization of Lipophilic Doxorubicin Pro-drug Micelles
Published on: August 2, 2016
Expansile crosslinked polymersomes for pH sensitive delivery of doxorubicin
Xifeng Liu1, Michael J Yaszemski1, Lichun Lu1
1Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN 55905, USA. Lu.Lichun@mayo.edu and Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USA.
Abstract:
We report a new crosslinked polymersome with pH-responsive swelling properties through acidic hydrolysis of hydrophobic contents from the amphiphilic polymer chains. Its unique stability under physiological conditions and large swelling capability under low pH conditions give this polymersome promising potential for anticancer drug delivery.
More Related Videos
Related Concept Videos
Site-Targeted Drug Delivery Systems: Polymeric Carriers
Modified-Release Drug Delivery Systems: Site-Targeted

