Related Experiment Video
Updated: Apr 1, 2026

04:59
Cheek Injection Model for Simultaneous Measurement of Pain and Itch-related Behaviors
Published on: September 27, 2019
13.3K
[A child with substantially itchy bumps on the back]
Marieke E C van Winden1, Sharon R P Dodemont, Herm Martens
1St. Elisabeth Ziekenhuis, afd. Chirurgie, Tilburg.
Nederlands Tijdschrift Voor Geneeskunde
|October 8, 2015
Summary
Papular urticaria, an itchy skin condition in children, is a hypersensitivity reaction to insect bites that can recur. Topical steroids and antihistamines may help manage symptoms.
Area of Science:
- Pediatric Dermatology
- Allergy and Immunology
Background:
- Papular urticaria is a common hypersensitivity reaction in children, often triggered by insect bites.
- Understanding the pathophysiology is crucial for effective management of recurrent episodes.
Observation:
- A 2-year-old boy presented with characteristic itchy papules and wheals.
- The clinical presentation was consistent with a diagnosis of papular urticaria.
Findings:
- Papular urticaria can manifest as relapsing episodes, even in the absence of ongoing insect exposure.
- The condition represents a delayed hypersensitivity response to arthropod bites.
Implications:
- Early diagnosis and appropriate management can alleviate patient discomfort and reduce disease recurrence.
- Further research into the immunological mechanisms may reveal novel therapeutic targets for papular urticaria.
Related Concept Videos
Acne Infection
50
Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
50
Skin Diseases and Disorders
6.2K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
6.2K
Skin Cancer
6.6K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
6.6K
Accessory Structures of the Skin: Hair and Hair Follicles
5.6K
Hair and hair follicles are integral components of the integumentary system. Hair is a filamentous structure composed mainly of a protein called keratin. It is found on the surface of the skin throughout the body, except for areas such as the palms of the hands and soles of the feet.
Hair is a keratinous filament growing out of the epidermis. It is primarily made of dead, keratinized cells. Hair strands originate at the epidermal penetration called the hair follicle. The hair shaft is the part...
Hair is a keratinous filament growing out of the epidermis. It is primarily made of dead, keratinized cells. Hair strands originate at the epidermal penetration called the hair follicle. The hair shaft is the part...
5.6K
Accessory Structures of the Skin: Sebaceous Glands
5.5K
A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
5.5K
Acute Pharyngitis
5.8K
Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
5.8K

