Related Experiment Video
Updated: Apr 1, 2026

The Mouse Stroke Unit Protocol with Standardized Neurological Scoring for Translational Mouse Stroke Studies
Published on: February 7, 2025
Evaluation of flat, angled, and vertical computer mice and their effects on wrist posture, pointing performance, and
1Synaptics, Inc., San Jose, CA, USA.
Background:
Modern computer users use the mouse almost three times as much as the keyboard. As exposure rates are high, improving upper extremity posture while using a computer mouse is desirable due to the fact that posture is one risk factor for injury. Previous studies have found posture benefits associated with using alternative mouse designs, but at the cost of performance and preference.
Objective:
To develop new computer mouse shapes, evaluate them versus benchmarks, and determine whether there are differences in wrist posture, pointing performance, and subjective measures.
Methods:
Three concept mice were designed and evaluated relative to two existing benchmark models: a traditional flat mouse, and an alternative upright mouse. Using a repeated measures design, twelve subjects performed a standardized point-and-click task with each mouse. Pointing performance and wrist posture was measured, along with perceived fatigue ratings and subjective preferences pre and post use.
Results:
All of the concept mice were shown to reduce forearm pronation relative to the traditional flat mouse. There were no differences in pointing performance between the traditional flat mouse and the concept mice. In contrast, the fully vertical mouse reduced pronation but had the poorest pointing performance. Perceived fatigue and subjective preferences were consistently better for one concept mouse.
Conclusions:
Increasing mouse height and angling the mouse topcase can improve wrist posture without negatively affecting performance.

