Related Experiment Video
Updated: Apr 1, 2026

Studying the Coding Profiles of Somatic Stimulation on Cardiac-locked Neuronal Responses in the Rat Spinal Dorsal Horn
Published on: May 23, 2025
Electrical Stimulation Able to Trigger Locomotor Spinal Circuits Also Induces Dorsal Horn Activity
Nejada Dingu1,2, Ronald Deumens3, Giuliano Taccola1,2
1Neuroscience Department, International School for Advanced Studies (SISSA), Trieste, Italy.
Objectives:
Investigate whether electrical stimulation of the spinal cord adapted to trigger locomotor patterns additionally influences dorsal horn networks.
Materials And Methods:
An in vitro model of isolated neonatal rat spinal cord was used to repetitively deliver electrical stimuli to lumbar dorsal roots and record from homolateral lumbar dorsal roots and ventral roots.
Results:
Repetitive electrical lumbar dorsal root stimulation can affect both locomotor rhythms derived from ventral neuronal circuits and activity from dorsal neuronal circuits.
Conclusion:
These data suggest that neuro-electrostimulation protocols can simultaneously activate functionally distinct spinal neuronal circuits.
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