Successful Translation of Fluorescence Navigation During Oncologic Surgery: A Consensus Report.

Area of Science:

• Surgical Oncology
• Medical Imaging
• Biotechnology

Background:

• Fluorescence guidance has emerged as a key technology in oncologic surgery over the past decade.
• Routine clinical adoption requires objective evaluation of its efficacy and value.
• This assessment is vital for regulatory approval and healthcare reimbursement.

Purpose of the Study:

• To critically evaluate imaging platform technology and optical imaging agents for fluorescence-guided surgery.
• To provide recommendations for developing successful clinical trials in oncologic surgery.
• To foster consensus within the surgical community on assessing this promising technique.

Main Methods:

• Consensus report based on a meeting of the International Society of Image Guided Surgery.
• Critical evaluation of existing fluorescence imaging platform technology.
• Review of optical imaging agents used in oncologic procedures.

Main Results:

• Identification of the need for objective assessment of fluorescence guidance benefits.
• Emphasis on characterizing procedural advantages over current surgical practices.
• Highlighting the importance of evaluating costs and safety risks associated with the technology.

Conclusions:

• Objective assessment of fluorescence guidance is essential for clinical integration and regulatory approval.
• Further research and clinical trials are needed to validate benefits, costs, and safety.
• Standardized evaluation protocols will facilitate the widespread adoption of fluorescence-guided oncologic surgery.