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Related Concept Videos

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Updated: Apr 1, 2026

High Resolution Quantification of Crystalline Cellulose Accumulation in Arabidopsis Roots to Monitor Tissue-specific Cell Wall Modifications
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Structure-function analysis identifies highly sensitive strigolactone receptors in Striga.

Shigeo Toh1, Duncan Holbrook-Smith1, Peter J Stogios2

  • 1Cell and Systems Biology, University of Toronto, 25 Willcocks Street, Toronto M5S 3B2, Canada.

Science (New York, N.Y.)
|October 10, 2015
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Summary
This summary is machine-generated.

Striga hermonthica strigolactone receptors exhibit high sensitivity, driven by larger binding pockets. This discovery enables a new bioassay for identifying strigolactone-altering chemicals and crops.

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Area of Science:

  • Plant Biology
  • Molecular Biology
  • Biochemistry

Background:

  • Strigolactones are crucial signaling molecules regulating plant development and interactions.
  • Parasitic plants like Striga hermonthica rely on strigolactones for host plant infestation.

Purpose of the Study:

  • To characterize the function and sensitivity of strigolactone receptors in Striga hermonthica.
  • To elucidate the structural basis for strigolactone sensitivity in parasitic plants.

Main Methods:

  • Chemical and structural biology techniques were employed.
  • Functional characterization of 11 strigolactone receptors from Striga hermonthica.
  • Crystal structure determination of a highly sensitive Striga strigolactone receptor.

Main Results:

  • Identified a clade of polyspecific strigolactone receptors in Striga.
  • Discovered a receptor sensitive to picomolar concentrations of strigolactones.
  • Revealed a larger binding pocket in the Striga receptor compared to Arabidopsis, explaining enhanced sensitivity.

Conclusions:

  • Striga's sensitivity to host strigolactones is mediated by its highly sensitive receptors.
  • The structural differences in receptors contribute to varying strigolactone sensitivity.
  • Developed a bioassay using Striga receptors in Arabidopsis for identifying chemicals and crops affecting strigolactone levels.