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In Vitro Fertilization

In Vitro Fertilization

In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...

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Related Experiment Video

Updated: Apr 1, 2026

Author Spotlight: Advancing Therapeutic Strategies for Improving Pregnancy Rates by Analyzing Embryo-Endometrium Interactions

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Predicting Embryo Presence and Viability.

K G Pohler¹, J A Green², T W Geary³

¹Department of Animal Science, University of Tennessee, Knoxville, TN, USA. kpohler@utk.edu.

Advances in Anatomy, Embryology, and Cell Biology

|October 10, 2015

Summary

This summary is machine-generated.

Detecting early pregnancy and embryo viability in mammals is crucial for reproductive success. New methods focus on identifying circulating biomarkers to predict embryonic presence and well-being in vivo.

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Area of Science:

Reproductive biology and veterinary sciences.
Mammalian reproduction and pregnancy diagnostics.

Background:

Successful mammalian reproduction requires precise timing of molecular, cellular, and physiological events from ovulation to live birth.
Early embryonic development and viability are critical, but pregnancy loss is common, impacting humans and livestock.
Current methods struggle to identify non-viable embryos early in gestation, leading to significant reproductive losses.

Purpose of the Study:

To review advances in predicting embryonic presence and viability in vivo.
To highlight the importance of early pregnancy detection for improved reproductive outcomes.
To discuss the identification of biomarkers in maternal circulation for assessing embryo health.

Main Methods:

Review of current scientific literature on in vivo methods for pregnancy detection and viability assessment.
Focus on the identification and analysis of products in maternal circulation.
Exploration of biomarkers indicative of embryonic presence and well-being.

Main Results:

Pregnancy establishment and live offspring birth are essential but complex processes in mammals.
A significant percentage of fertilized oocytes do not result in live birth due to pregnancy loss.
Research is advancing towards identifying circulating markers for early embryo detection and viability assessment.

Conclusions:

Early detection of embryonic presence and viability is critical for successful reproduction in mammals.
Identifying biomarkers in maternal circulation offers a promising avenue for non-invasive assessment of embryo health.
Continued research in this area can improve prenatal care and livestock management, reducing reproductive losses.