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Published on: June 18, 2020
Carbon-Dot-Based Nanosensors for the Detection of Intracellular Redox State
Ye Liu1, Ye Tian1, Yefei Tian1
1State Key Laboratory of Molecular Engineering of Polymers and Department of Macromolecular Science, Fudan University, Shanghai, 200433, P. R. China.
Abstract:
Carbon-dot-based nanosensors are prepared through sequentially assembling a polymer/carbon dot multilayer shell on mesoporous silica nanoparticles with different crosslinking densities of disulfide bonds; they can be utilized to evaluate the gluthathione (GSH) concentration. In vitro cell assays demonstrate the feasibility of using such nanosensors in evaluating the intracellular redox state of different cells.
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