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Related Concept Videos

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

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Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

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As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
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Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
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Pharmacodynamics in Geriatric Patients: Effects of Age01:27

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Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

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In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
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Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
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[Esthetic dermatology for the elderly].

U Wollina1, A Goldman2

  • 1Klinik für Dermatologie und Allergologie, Krankenhaus Dresden-Friedrichstadt, Städtisches Klinikum, Akademisches Lehrkrankenhaus der TU Dresden, Friedrichstr. 41, 01067, Dresden, Deutschland. wollina-uw@khdf.de.

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|October 11, 2015
PubMed
Summary

Aesthetic dermatology requires modified techniques for the elderly, focusing on the aging face. Regenerative medicine principles enhance outcomes in geriatric skin care.

Keywords:
Botulinum toxinFillerLaserPeelingPhotodynamic therapy

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Area of Science:

  • Dermatology
  • Gerontology
  • Regenerative Medicine

Background:

  • Aging presents unique challenges for esthetic dermatology.
  • Standard dermatological procedures may not be suitable for elderly patients.
  • The aging face requires specialized consideration in esthetic treatments.

Purpose of the Study:

  • To discuss the specific needs of elderly patients in esthetic dermatology.
  • To highlight modifications required for established dermatological techniques.
  • To emphasize the role of regenerative medicine in geriatric esthetic care.

Main Methods:

  • Review of current esthetic dermatology techniques.
  • Analysis of age-related facial changes.
  • Integration of regenerative medicine principles.

Main Results:

  • Established esthetic methods need adaptation for older individuals.
  • Regenerative medicine offers promising approaches for the aging face.
  • Tailored treatments improve esthetic outcomes in the elderly.

Conclusions:

  • Esthetic dermatology for the elderly necessitates modified techniques.
  • Regenerative medicine is key to successful esthetic outcomes in older patients.
  • Focusing on the aging face with specialized approaches is crucial.