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Updated: Apr 1, 2026

Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System
Published on: May 24, 2017
Particulate Matter from Electronic Cigarettes and Conventional Cigarettes: a Systematic Review and Observational
Esteve Fernández1,2,3, Montse Ballbè4,5,6, Xisca Sureda7,8,9
1Tobacco Control Unit, Cancer Prevention and Control Program, Institut Català d'Oncologia, WHO Collaborating Center for Tobacco Control, L'Hospitalet de Llobregat, Barcelona, Spain. efernandez@iconcologia.net.
Objectives:
The aim of this study is to review the literature on the composition of aerosols from electronic cigarettes (e-cigarettes) originated by human vaping and to describe the emission of particulate matter ≤ 2.5 μm in diameter (PM(2.5)) from conventional and e-cigarettes at home in real-use conditions.
Methods:
We conducted a systematic literature search in PubMed and Web of Science. We measured PM(2.5) in four different homes: one from a conventional cigarette smoker, one from an e-cigarette user, and two from non-smokers.
Results:
The review identified eight previous investigations on the composition of aerosols from e-cigarettes originated by human vaping and indicated that emissions from e-cigarettes can contain potential toxic compounds such as nicotine, carbonyls, metals, and organic volatile compounds, besides particulate matter. In the observational study, the PM(2.5) median concentration was 9.88 μg/m³ in the e-cigarette user home and 9.53 and 9.36 μg/m³ in the smoke-free homes, with PM(2.5) peaks concurrent with the e-cigarette puffs.
Conclusion:
Both the literature review and the observational study indicate that e-cigarettes used under real-conditions emit toxicants, including PM(2.5). Further research is needed to characterize the chemicals emitted by different types of e-cigarettes and to assess secondhand exposure to e-cigarette aerosol using biological markers.
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