Highly sensitive determination of chloramphenicol based on thin-layered MoS2/polyaniline nanocomposite

The nanocomposite of molybdenum disulfide (MoS2) and polyaniline (PANI) was prepared through in situ polymerization of aniline on the surface and interlayer of thin-layered MoS2. Owing to the physisorption of aromatic aniline onto the basal plane of MoS2, the electrochemical properties of MoS2/PANI nanocomposite were improved. And a novel electrochemical sensor based on MoS2/PANI nanocomposite was used to determine chloramphenicol by differential pulse voltammetry, exhibiting excellent performance. The detection range was from 1×10(-7) mol L(-1) to 1×10(-4) mol L(-1), with a high sensitivity and a low detection limit of 6.9×10(-8) mol L(-1). In addition, this sensor can be used for the determination of chloramphenicol in real samples.