Reactions of isolated persulfides provide insights into the interplay between H2S and persulfide reactivity
T Spencer Bailey1, Michael D Pluth1
1Department of Chemistry and Biochemistry, Institute of Molecular Biology, Materials Science Institute. University of Oregon, Eugene, OR 97403, USA.
Abstract:
Hydrogen sulfide is ubiquitous in biological systems and exerts function over a wide range of important physiological processes. Complementing free H2S, the reductant-labile sulfur pool plays significant roles in the translocation and action of sulfide, however the chemistry of reductant-labile sulfide sources has not been studied systematically. Using a combination of NMR and UV-Vis spectroscopy, we investigated the spectroscopic properties and reactivity of three isolated organic persulfides and report a simple model for persulfide reactivity, including their roles as nucleophiles, electrophiles, and sulfide donors.
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