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Updated: Apr 1, 2026

Efficient and Consistent Generation of Retinal Pigment Epithelium/Choroid Flatmounts from Human Eyes for Histological Analysis
Published on: October 28, 2022
[Epiretinal membranes]
B Dupas1, R Tadayoni1, A Gaudric1
1Service d'ophtalmologie, hôpital Lariboisière, AP-HP, université Paris 7 - Sorbonne Paris Cité, 2, rue Ambroise-Paré, 75475 Paris cedex 10, France.
Abstract:
Idiopathic epiretinal membranes represent a common condition, and are present in approximately 10% of people over the age of 70 years. They are idiopathic in 80% of cases, or may be secondary to various conditions such as a prior retinal detachment, or vascular or inflammatory retinal diseases. The main symptoms are visual loss and metamorphopsia. The diagnosis of epiretinal membrane is currently facilitated by OCT, which provides prognostic and therapeutic decision-making assistance. Surgery for epiretinal membranes is currently well codified through sutureless vitrectomy and dyes. Dissection of the membrane (with or without associated peeling of the internal limiting membrane) ensures good anatomical and functional results, while being relatively minimally invasive.
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