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Updated: Jan 13, 2026
![PET/CT With [68Ga]-NOTA-FAP-2286 for Imaging of Tendon Injuries in Rat Achilles Tendon Injury Models](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F67717.jpg&w=3840&q=50)
PET/CT With [68Ga]-NOTA-FAP-2286 for Imaging of Tendon Injuries in Rat Achilles Tendon Injury Models
Published on: June 6, 2025
Incidental Detection of Femoral Pseudoaneurysm at 18F-FDG PET/CT
Stephanie Nougaret1, Monica Ragucci, Ariadne M Bach
1From the *Department of Diagnostic Imaging, St Eloi Hospital, Montpellier; †IRCM, Institut de Recherche en Cancérologie de Montpellier, Montpellier, France; ‡Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY; §IRCCS SDN, Naples, Italy; and ∥Saint Vincent Ferrer High School, New York, NY.
Abstract:
A 72-year-old man with history of lung cancer and melanoma was referred for routine follow-up with 18F-FDG PET/CT. CT images showed a new mass in the right groin associated with mild FDG activity on 18F-FDG PET images. Subsequent ultrasound obtained the same day demonstrated flow within the lesion to be a pseudoaneurysm of the right femoral artery.
Insights
A new groin mass in a patient with cancer history was initially concerning. However, imaging revealed it was a pseudoaneurysm of the right femoral artery, not cancer recurrence.
Area of Science:
- Oncology
- Vascular Surgery
- Radiology
Background:
- Patients with a history of cancer, such as lung cancer and melanoma, require careful monitoring for potential recurrence or new pathologies.
- 18F-FDG PET/CT is a valuable imaging modality for detecting metabolically active lesions, often used in cancer follow-up.
Purpose of the Study:
- To report a case where a new mass identified on 18F-FDG PET/CT in a cancer patient was ultimately diagnosed as a vascular anomaly.
- To highlight the importance of integrating different imaging modalities for accurate diagnosis.
Main Methods:
- A 72-year-old male patient with a history of lung cancer and melanoma underwent routine follow-up using 18F-FDG PET/CT.
- Computed tomography (CT) revealed a new right groin mass with mild fluorodeoxyglucose (FDG) uptake.
- Ultrasound with Doppler was performed to further characterize the lesion.
Main Results:
- The CT component of the 18F-FDG PET/CT demonstrated a new mass in the right groin.
- Mild FDG activity was noted within the mass on the PET images.
- Ultrasound confirmed the presence of flow within the lesion, identifying it as a pseudoaneurysm of the right femoral artery.
Conclusions:
- A new focal uptake on 18F-FDG PET/CT in a cancer patient does not always indicate malignancy.
- Vascular abnormalities, such as pseudoaneurysms, can mimic malignant lesions on PET/CT.
- Ultrasound is crucial for differentiating vascular lesions from true neoplastic processes.
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