Mesenteric Panniculitis Demonstrated on 18F-FDG PET/CT

Domenico Albano1, Giovanni Bosio, Francesco Bertagna

  • 1From the *Nuclear Medicine, Spedali Civili Brescia, and †Nuclear Medicine, University of Brescia, Brescia, Italy.

Clinical Nuclear Medicine
|October 14, 2015
PubMed

Insights

Mesenteric panniculitis, an inflammatory condition, can be challenging to diagnose due to non-specific symptoms. Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT) aids in diagnosing this condition by showing characteristic metabolic activity.

Area of Science:

  • Gastroenterology
  • Radiology
  • Nuclear Medicine

Background:

  • Mesenteric panniculitis is an inflammatory condition affecting mesenteric adipose tissue.
  • Its etiology is unknown, and clinical symptoms like abdominal pain and fever are non-specific, complicating diagnosis.

Observation:

  • A 48-year-old man presented with persistent abdominal pain and fever unresponsive to initial treatments.
  • A computed tomography (CT) scan was inconclusive.
  • An F-FDG PET/CT scan was performed for further investigation.

Findings:

  • The F-FDG PET/CT scan revealed uniformly high uptake of F-FDG in the mesenteric adipose tissue.
  • This uptake was observed across the mesocolon, mesoappendix, mesosigmoid, and mesorectum.

Implications:

  • F-FDG PET/CT can be a valuable diagnostic tool for mesenteric panniculitis.
  • This imaging modality can help identify characteristic metabolic patterns in affected mesenteric tissues.
  • Early and accurate diagnosis can potentially lead to better patient management.

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