Enhanced Biodegradability of Pharmaceuticals and Personal Care Products by Ionizing Radiation
Hyun Young Kim1, O-Mi Lee, Tae-Hun Kim
1Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, 29 Geumgu-gil, Jeongeup-si, Jeollabuk-do, 580-185, Rep. of Korea.
Abstract:
The radiolytic degradation of antibiotic compounds, including lincomycin (LMC), sulfamethoxazole (SMX), and tetracycline (TCN), and the change of biodegradability of the radiation-treated target compounds were evaluated. As a result, the degradation of target antibiotics by hydrolysis, biodegradation, and gamma irradiation showed a compound-dependent manner. However, the biodegradability of all target compounds was enhanced by the gamma irradiation. The enhanced biodegradability after gamma irradiation (2 kGy) followed the trend of LMC (18.89%)
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