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Updated: Mar 31, 2026

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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Developing structure-activity relationships from an HTS hit for inhibition of the Cks1-Skp2 protein-protein

Rajinder Singh1, Arvinder Sran1, David C Carroll1

  • 1Rigel Pharmaceuticals Inc., 1180 Veterans Boulevard, South San Francisco, CA 94080, USA.

Bioorganic & Medicinal Chemistry Letters
|October 15, 2015
PubMed

Keywords:
Anti-cancerE3 ubiquitin ligasesProtein–protein interactionsStructure–activity relationshipsp27

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